If your sister or mother also has PCOS, you may be more likely to have it. It might also be connected to issues that cause your body to create excessive amounts of insulin, which could harm your ovaries and prevent them from ovulating (or release eggs). Low-grade chronic inflammation can also be involved. The molecules that white blood cells make to fight infection can trigger the ovaries to create androgens. The majority of PCOS patients have excessive levels of androgens. Transgender guys are much more likely to develop PCOS. There may or may not be a role for hormone therapy in that. This is so because there are so many additional factors that affect PCOS, such as insulin resistance, metabolic syndrome, and excessive levels of androgens.
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